Cultural foundations of a mathematician's thinking: a Psychobiographical exploration of Zoltán Paul Dienes and his cognitive development.

This psychobiographical study utilises Lev Vygotsky's sociocultural theory to explore the impact of diverse cultural experiences on the intellectual growth of Zoltán Paul Dienes, a prominent mathematician and theorist of mathematical education. Vygotsky's sociocultural theory is particularly relevant for understanding the impact of culture on intellectual development. According to Vygotsky, cognitive development is shaped by social and cultural interactions, and the tools and practices of a given culture. The study employs a taxonomy of cognitive tools to categorise the influences young Dienes encountered in Hungary, Austria, France, United Kingdom and elsewhere. By examining the presence and frequency of these tools in his formative years, the research sheds light on the origins of Dienes's principles in mathematical education. The research enriches psychobiography by integrating sociocultural theory, providing valuable insights into the relationship between culture, cognitive tools, and intellectual growth in knowledgeable individuals. Ultimately, this study contributes to a better comprehension of the origins and principles behind Dienes's theory of mathematical education.

Triple Antioxidant Therapy, an Alternative for Patients with Chronic Liver Disease - A Prospective Multicenter Interventional Study.

Background: Non-alcoholic fatty liver disease (NAFLD) has increased exponentially in recent years in Western European countries, where the number of hepatitis of viral etiology has been declining, and it is thought to be the most common cause of chronic liver disease in the near future (1). Currently, NAFLD is both the second most common cause of hepatocellular carcinoma (HCC) and the second most common indication for liver transplantation (2-4). This problem is very serious, as cases of NAFLDs are increasingly in children, a population with a long life ahead, and in whom the disease has all the time to progress to cirrhosis and HCC (5, 6). Objectives: The goal of this prospective study is to determine the effect of an original formula consisting in silymarin, organic selenium and alpha lipoic acid, in reducing liver damage in patients with chronic liver disease. Material and methods: The study started in March 2018, initially with a group of patients from Bucharest, integrated in the study at St. Mary's Hospital. In October 2018 it was expanded at the national level to 1 718 patients, monitored by 145 investigating physicians from 134 centers, with an average of 11.8 patients per investigating physician. Outcomes: Taking each stage of fatty liver disease (FLD) at T0 moment (the beginning of the study), we observed that 25% of patients with grade I FLD had no sign of disease at the end of the study, 74% of those with grade II FLD recovered or improved their health, and 83% of patients with grade III FLD recovered or improved their health. There were 149 patients with no FLD detected at the end of the study (recovered). Conclusion: Based on triple antioxidant therapy, the original formula improved the evolution and prognosis of patients with chronic liver disease.